NILOTINIB-INDUCED DYSTONIA AND COGNITIVE DEFICITS IN A NEUROLOGICALLY NORMAL PATIENT WITH CHRONIC MYELOID LEUKEMIA

Nilotinib-Induced Dystonia and Cognitive Deficits in a Neurologically Normal Patient with Chronic Myeloid Leukemia

Nilotinib is a tyrosine kinase inhibitor used to treat patients with chronic myeloid leukemia (CML).This agent is also being studied in neurodegenerative disorders including Parkinson disease.Studies GARLIC RICH have shown that nilotinib may decrease the accumulation of parkin substrates and decrease the loss of dopaminergic cells.The use of niloti

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Impact Analysis of Connecting Passage Shield Method Construction on Interval Shield Tunnel in High-confined Aquifer Soft Soil Area

Objective During the construction of shield method connecting passage, the jacking and cutting actions cause significant changes in the stress Ceiling Fan Accessory at tunnel intersection, exacerbating the impact of breakthroughs and reducing safety performance.To efficiently achieve construction control, it is necessary to conduct an in-depth stud

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